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- 2019
Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped DimerDOI: https://doi.org/10.1016/j.str.2018.10.025 Abstract: ？ The active and inactive HPK1 kinase in apo and ligand bound forms are characterized ？ Structures show rare domain-swapped dimer involving helical activation segment ？ Dimerization observed in solution suggesting potential biologically relevance ？ Ligand complex structure provides insights for structure-based drug desig
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