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OALib Journal期刊
ISSN: 2333-9721
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-  2019 

The Different Effects of Substrates and Nucleotides on the Complex Formation of ABC Transporters

DOI: https://doi.org/10.1016/j.str.2019.01.010

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Abstract:

? Intact complexes of two ABC transporters are observed using native mass spectrometry ? Substrate and nucleotide binding affects the formation and stability of the complexes ? Molybdate is needed to allow docking of ModA onto the transporter ModBC ? ATP acts synergistically with vitamin B12 to destabilize the BtuCD-F comple

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