Muscle Stem Cells Give Rise to Rhabdomyosarcomas in a Severe Mouse Model of Duchenne Muscular Dystrophy

？ Dystrophic disease progression accelerates rhabdomyosarcoma (RMS) formation ？ MuSCs carry a gene signature characteristic of RMSs before tumor formation ？ Increased self-renewal contributes to dystrophic MuSCs transformation ？ Dystrophic MuSCs induce the development of RMS in viv