Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination

？ FANCD2 colocalizes with co-transcriptional R-loops in human cells ？ Human FANCI-FANCD2 robustly binds ssRNA, but not RNA:DNA hybrids ？ Human FANCI-FANCD2 binds R-loops via the displaced ssDNA strand and ssRNA tail ？ ssRNA and R-loop can stimulate robust FANCI-FANCD2 monoubiquitinatio