The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization

？ Single B cell sorting defined HIV neutralizing antibody response of immunized guinea pigs ？ The C3/V4 region of the HIV envelope glycoprotein is a significant immune target ？ Three N-linked glycosylation sites in C3/V4 are essential for defined antibody response ？ Sera from other immunized animals and HIV-infected people contain similar antibodie