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-  2019 

Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development

DOI: https://doi.org/10.1016/j.celrep.2019.04.083

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Abstract:

? scRNA-seq of hESC differentiation into β cells in vitro ? Progenitor and endocrine compartments express different WNT pathway components ? APC deletion in mouse endocrine precursors prevents endocrine differentiation ? Small molecule inhibition of the WNT pathway in vitro increases endocrine yiel

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