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- 2019
The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding RegulationDOI: https://doi.org/10.1016/j.str.2018.10.005 Abstract: ？ SPOP binding to Pdx1 regulates β cell survival and insulin homeostasis ？ The co-structure of SPOP/Pdx1 shows features distinct from other SPOP ligands ？ Affinity of Pdx1 to SPOP is altered by Pdx1 phosphorylation in the binding sit
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