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-  2019 

A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases

DOI: https://doi.org/10.1016/j.isci.2019.01.023

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Abstract:

? TGF-β1 extensively impairs GC activity ? Phospho-cofilin1 is a key link in TGF-β1 signaling cascade subserving GC insensitivity ? Phospho-cofilin1-activated phospholipase D (PLD) reduces GC activity ? SMRT induction downstream of PLD mediates TGF-β1 impairment of GC activit

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