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-  2019 

A Human Induced Pluripotent Stem Cell-Derived Tissue Model of a Cerebral Tract Connecting Two Cortical Regions

DOI: https://doi.org/10.1016/j.isci.2019.03.012

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Abstract:

? A cerebral tract model was generated from iPS cell-derived cortical spheroids ? Two spheroids were spontaneously connected with an axon fascicle in a microdevice ? An axon fascicle electrically connected two cortical spheroids ? Knockdown of L1CAM disrupted axon fascicle formation in the model tissu

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