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-  2019 

Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity

DOI: https://doi.org/10.1016/j.celrep.2019.03.037

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Abstract:

? Inactivation of T cell autophagy results in enhanced tumor rejection ? T cells deficient in autophagy show increased glucose uptake and lactate production ? Reduction in SAM transcriptionally reprograms immune cells toward effector memor

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