Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging

？ Transcriptome-based age classifiers can distinguish young versus old tissues ？ Application of age classifiers to drug-induced transcriptomes finds geroprotectors ？ Validation of geroprotectors in C. elegans highlights Hsp90 inhibitors ？ Hsp90 inhibitors act through HSF-1 to improve health and extend lifespa