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OALib Journal期刊
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-  2019 

The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae

DOI: https://doi.org/10.1016/j.cub.2018.11.066

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Abstract:

? YAP/TAZ are critical for CAVIN1 and CAVEOLIN1 expression and caveolae formation ? The essential caveolar genes CAVIN1 and CAVEOLIN1 are direct YAP/TAZ-TEAD target genes ? YAP/TAZ are hyperactivated in caveolae-deficient cells ? Caveolae facilitate YAP/TAZ-mediated shear stress respons

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