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-  2019 

Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability

DOI: https://doi.org/10.1016/j.cub.2018.11.053

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Abstract:

? A super-resolution microscopy screen reveals filopodia core and accessory proteins ? FAK and paxillin are accessory, and not core, components of filopodia tip adhesions ? PI(3,4)P2 is the prominent phosphatidylinositol species enriched at filopodia tips ? p130Cas is a mechanosensitive regulator of filopodia stabilit

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