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-  2019 

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

DOI: https://doi.org/10.1016/j.chom.2018.12.005

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Abstract:

? The mAb cocktail MBP134 AF protects ferrets from lethal EBOV, SUDV, and BDBV challenge ? A single 25-mg/kg dose of MBP134 AF protects NHPs challenged with EBOV, SUDV, and BDBV ? Both CHOK1-AF cell-produced and plant-produced MBP134 AF is therapeutically effectiv

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