全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...
-  2019 

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

DOI: https://doi.org/10.1016/j.ccell.2019.01.004

Full-Text   Cite this paper   Add to My Lib

Abstract:

? Promoter CpG islands display asymmetric border methylation encroachment in cancer ? 5hmC is enriched in normal cells at CpG island shores prone to methylation spread ? H3K4me1 patterns at CpG island borders are associated with the mode of encroachment ? H3K4me1 disruption results in DNA methylation alterations at island border

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133