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- 2019
An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular CytotoxicityDOI: https://doi.org/10.1016/j.chom.2019.03.002 Abstract: ？ HIV Env exists in several conformations, including an asymmetric State 2A ？ State 2A is difficult to trigger and is susceptible to non-neutralizing antibody attack ？ Sera from HIV+ individuals contain antibodies that can stabilize Env State 2A ？ Conditions triggering State 2A expose epitopes that induce ADC
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