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-  2019 

ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome

DOI: https://doi.org/10.1038/s41423-019-0201-9

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Abstract:

Anti-citrullinated protein antibodies (ACPAs) are a group of autoantibodies targeted against citrullinated proteins/peptides and are informative rheumatoid arthritis (RA) biomarkers. ACPAs also play a crucial role in RA pathogenesis, and their underlying mechanism merits investigation

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