The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: a large study from a single institution

Previous studies have reported up to 50% of ductal carcinoma in situ (DCIS), is HER2 positive, but the frequency of HER2-positive invasive breast cancer (IBC) is lower. The aim of this study is to characterise HER2 status in DCIS and assess its prognostic value