Management beyond Insulin in Gestational Diabetes Mellitus: A Review Update

Hyperglycemia is the most common endocrine disorder of pregnancy. As compared to Diabetes in pregnancy(DIP) the management of gestational DM(GDM) has always been a topic of controversy. Medical nutrition therapy(MNT) is the cornerstone of GDM management. 80-90% of GDM mothers can be treated by MNT alone and the rest will require drugs. Considerable controversy surrounds the use of oral anti-diabetic medications in pregnancy. The most widely studied drugs are glyburide and metformin. Conflicting results have been produced by different studies. However recent meta-analyses have shown that they can be an attractive alternative to insulin if long term safety data become available. Till then it might be too early to make a final comment on their use in GDM. Journal of National Institute of Neurosciences Bangladesh, 2018;4(2): 145-149