Clinical Application of Fecal Drugs in China

Objective: There is a limited knowledge regarding faecal microbial therapy in modern Western medicine. However, stool has been widely used clinically in the world and it is a relatively mature therapy in ancient China. It has the potential value on the study of gastrointestinal microflora and faecal micro-ecological transplantation. And the clinical experience on stool therapy in ancient China might be useful for the current faecal bacterial transplantation therapy worldwide. Design: The therapy discusses clinical evidences on the use of faeces in ancient China, including donor selection, faeces processing, preservation and its clinical application, including dosage, contraindications and side-effects., but the patients ware not involved. There are faecal transplant breakthroughs on the cognitive. Results: This review describes the different methods of prepareing and processing faecal drugs and the extensive practical treatment applications. It also clarify the ancient techniques for the potential uses of modern faecal medicine. Furthermore, this review will be of interest because of it discusses an emerging area of modern medicine and its bases in traditional Chinese medicine (TCM). Conclusion: The analysis on Natural condition selection, nutritional conditioning and medical evaluation of faecal donor will improve the faecal microflora extraction and promote its mechanism research. It gives us a new sight to understand on distribution of functional bacteria and influencing factors of gastrointestinal microflora. Combined the microflora with equipment, air, soil, additives and foods in the process of faecal processing, it prompt us to re-understand the intestinal nutrition, the faecal microflora and human ecosystem. Meanwhile, the clinical validity of faecal microflora and pathogenesis based on accumulation of clinical practice evidences on the use of faeces in ancient China might be useful for current faecal bacterial transplantation study worldwide