A Review of the Molecular Pathways of Oncogenic HPV and Targeted the Rapies in Carcinoma of the Uterine Cervix

Cervical carcinoma is a preventable disease based on its etiopathogenesis. This relies highly on its prompt diagnosis and treatment based on effective screening and treatment methods. Knowledge of its molecular pathways will drive the use of targeted therapies in the treatment of the disease. The objectives of this review are: to explore the biology and immunology of HPV; the various molecular pathways through which oncogenic HPV destroys normal cervical cells; and targeted therapies. Several molecular pathways have been identified but the use of drugs to act on specified molecular targets are at different stages of clinical trials.