Pulmonary and Rifampicin-Resistant Tuberculosis Associated with Human Immunodeficiency Virus Infection Prevalence in Bayelsa State, Nigeria: A Case of Patients Attending Federal Medical Centre Yenagoa

This study investigated the prevalence of pulmonary tuberculosis (PTB) associated human immunodeficiency virus/ acquired immunodeficiency syndrome (HIV/AIDs) infection among patients attending Federal Medical Centre Yenagoa, Bayelsa state, Nigeria. Out of the 456 subjects recruited for the study, 88 patients (comprising of male and females) with known cases of PTB was studied for the association of HIV with PTB. Blood and sputum samples were collected following standard procedure. HIV/AIDS was determined following serial all logarithm test viz: Determine, Unigold, Stat pack, while the PTB and rifampicin resistant tuberculosis (RMPR – TB) was analyzed using GeneXpert System. Results showed that 41(9.0%) and 47 (10.3%) was seropositive and seronegative to HIV/AIDS. There was no significant difference (P>0.01) among the serotypes/groups. Also 0.7% of the PTB subjects with HIV were resistant to rifampicin. Therefore, there is the need for surveillance of drug resistance in tuberculosis which could lead strengthening of laboratory networks and enhance its prevention and control