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-  2019 

Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor

Keywords: Dysembryoplastic Neuroepithelial Tumors (DNET), Intractable Epilepsy, Electrocorticogram (ECoG), Surgery, Extended Resection

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Abstract:

Objective Investigating the surgical treatment for dysembryoplastic neuroepithelial tumor. Methods A total of 12 cases (7 males, 5 females, aged 4~36 years) of dysembryoplastic neuroepithelial tumors from 2010 to 2014 in Shanghai Blue Cross Brain Hospital were analyzed retrospectively, including 9 cases of temporal lobe tumor, 2 cases of frontal lobe tumor, and 1 case of parietal lobe tumor. The tumors and epileptogenic foci outside the lesions were resected under the guidance of electrocorticogram in all patients. Results The pathological examination showed that all the tumors were dysembryoplastic neuroepithelial tumors. All the patients had been followed up for 2 to 4 years. Epilepsy occurred in 2 patients and the others were seizure free after the surgery. No tumor recurrence occurred during the follow-up. Conclusion Dysembryoplastic neuroepithelial tumor is a benign tumor often causes intractable epilepsy, which can be controlled by the extended excision of the tumors and epileptogenic cortex under the guidance of electrocorticogram

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