The Examination of the Actual State of Autosomal Dominant Polycystic Kidney Disease Treatment at Our Hospital

Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of inherited kidney disease. Approximately half of ADPKD patients reach end-stage renal failure by 60 years of age. ADPKD can also cause severe complications, so continuous follow up is necessary. We aimed to develop a strategy for future ADPKD practice based on the current situation of ADPKD practice at our hospital . Methods : From February 2002 to April 2016, 81 cases with ICD-10 codes related to ADPDK were registered, based on the patients’ medical records. The patients were divided into four groups according to the outcome after their introduction to our hospital . Various parameters at the first visit were compared and examined. We also investigated 19 patients who were newly introduced from May 2016 to September 2017. Results :We encountered to the fact that most ADPKD patients weren’t introduced to our department (Division of Nephrology) until end stage renal failure, which unable both proactive treatment and evaluating severe complications. We coped with this problem and succeeded to have more ADPKD patients in the early stage. Conclusion: Now that we have more ADPKD patients in the early stage, we would like to treat ADPKD by proactive practices (i.e., introduce Tolvaptan treatment for adaptation cases) at the proper timing, and at the same time, offer them continuous medical follow ups for severe complications. Eventually, we hope to develop a sufficient strategy for future ADPKD practice which we could not reach this time