Evaluation of Serum Calcium, Phosphorus and Progesterone in Post-Menopausal Women in Khartoum State-Sudan

Objective: This study was conducted to show importance of preventive measures like calcium supplementation or hormonal therapy to prevent fractures. Material and Methods: This is a comparative (analytical study), case control study. This study includes 50 blood samples, a 30 blood samples were collected from Sudanese post menopause women in a period between March to June 2018, chosen randomly from Umdwanban village, and 20 apparently healthy individuals as control to assess the effect of post menopause on calcium, phosphorus and progesterone. Self-administered questionnaire was used to collect the data. Three ml of venous blood were collected by using sterile disposable syringes and poured into lithium heparin containers, immediately centrifuged and plasma separated transferred in a plain container and processed. Stored at-20°C until analysis. These samples were evaluated for the serum levels of calcium and phosphorus determined by colorimeter and progesterone by Tosoh AIA 360, and the obtained results were analyzed by SPSS. Results: The study results showed that serum level of calcium and phosphorus was significantly changed (p<0.05) in post menopause women, the serum level of calcium is decreased and phosphorus is increased in post menopause women. The mean of serum calcium was 6.733 in test group and 8.955 in control group with p.value of 0.029 and the mean of serum phosphorus was 5.570 in test group and 3.480 in control group with p.value of 0.031. And show a non-significant difference in the serum level of progesterone between the test group and control group (P-value =0.447). Also the study showed the age and social status of the post menopause women have no effect on the serum level of calcium, phosphorus and progesterone. Conclusion: This study concluded that the serum level of calcium is decrease and phosphors is increase while progesterone is unaffected. And the age and social status of post menopause have no effect on the serum level of calcium, phosphors and progesterone