Introduction: Malaria is a febrile illness caused by the Plasmodium species. The mangrove swamp forest vegetation and high annual rainfall characteristic of the Niger Delta region of Nigeria encourage all year round transmission of malaria. This study aimed to determine the prevalence and speciation of Plasmodium parasitaemia among pregnant women in the Niger Delta region of Nigeria. Methodology: Cross-sectional study carried out in three states of the Niger Delta region; Akwa-Ibom, Delta and Rivers between April and June 2019. Study Sites were chosen by stratified random sampling. Demographic information was collected using pretested interviewer-administered questionnaires via the Open Data Kit application on android mobile phones. Diagnosis was by rapid diagnostic test (RDT) and Microscopy. Ethical approval and informed consent were obtained. Data was analyzed using the SPSS v25 software. Chi-square statistic and Fischer’s exact test were used to compare data, all at a 95% confidence interval and significance level of 0.05. Results: Two thousand, eight hundred and twenty (2820) pregnant women were studied; 948, 992 and 880 from Akwa-Ibom, Delta and Rivers respectively. Overall prevalence of parasitaemia using RDT and Microscopy was 6.8% and 6.7% respectively. All except 1% of malaria was attributed to falciparum species. The other species were plasmodium ovale and plasmodium malariae. Conclusion: The prevalence of Plasmodium parasitaemia among pregnant women in the Niger Delta region of Nigeria has reduced considerably, giving credence to the malaria preventive strategies applied in antenatal care. When properly stored and used as recommended, malaria RDTs compare favorably with microscopy; therefore, no case of malaria should be missed due to a facility’s incapability to carry out microscopic diagnosis.
References
[1]
Sutherland, C.J., Tanomsing, N., Nolder, D., Oguike, M., Jennison, C., Pukrittayakamee, S., Dolecek, C., Hien, T.T., Do Rosario, V.E., Arez, A.P., Pinto, J., Michon, P., Escalante, A.A., Nosten, F., Burke, M., Lee, R., Blaze, M., Otto, T.D., Barnwell, J.W., Pain, A., Williams, J., White, N.J., Day, N.P., Snounou, G., Lockhart, P.J., Chiodini, P.L., Imwong, M. and Polley, S.D. (2010) Two Nonrecombining Sympatric Forms of the Human Malaria Parasite Plasmodium ovale Occur Globally. The Journal of Infectious Diseases, 201, 1544-1550. https://doi.org/10.1086/652240
[2]
Oguike, M.C., Betson, M., Burke, M., Nolder, D., Stothard, J.R., Kleinschmidt, I., Proetti, C., Bousema, T., Ndounga, M., Tanabe, K., Ntege, E., Culleton, R. and Sutherland, C.J. (2011) Plasmodium ovale Curtisi and Plasmodium ovale Wallikeri Circulate Simultaneously in African Communities. International Journal for Parasitology, 41, 677-683. https://doi.org/10.1016/j.ijpara.2011.01.004
[3]
Kasso, T., Oboro, I.L., Maduka, O., Awopeju, A.T.O., Paul, N.I., Yaguo-Ide, L.E., Chijioke-Nwauche, I.N., Ogoro, M., Otto, G. and Nwauche, C.A. (2019) Malaria Preventive Practices among Pregnant Women in Akwa Ibom State, Southern Nigeria. Archives of Current Research International, 19, 1-8. https://doi.org/10.9734/acri/2019/v19i330158
[4]
Sitali, L., Chipeta, J., Miller, J.M., Moonga, H.B., Kumar, N., Moss, W.J. and Michelo, C. (2015) Patterns of Mixed Plasmodium Species Infections among Children Six Years and under in Selected Malaria Hyper-Endemic Communities of Zambia: Population-Based Survey Observations. BMC Infectious Diseases, 15, 204. https://doi.org/10.1186/s12879-015-0935-7
[5]
National Malaria Elimination Program (Nigeria), and ICF International (2016) 2015 Nigeria Malaria Indicator Survey: Atlas of Key Indicators. National Malaria Elimination Program (Nigeria), and ICF International, Rockville. https://dhsprogram.com/pubs/pdf/ATR17/ATR17.pdf
[6]
Association for Reproductive and Family Health. World Malaria Day 2018: How Nigeria Can Beat Malaria for Good. https://arfh-ng.org/world-malaria-day-2018-how-nigeria-can-beat-malaria-for-good
[7]
WHO, World Malaria Report 2019. https://www.who.int/publications/i/item/9789241565721
[8]
Federal Ministry of Health (2015) Malaria Indicator Survey (MIS). Abuja.
[9]
Jukes, M.C., Pinder, M., Grigorenko, E.L., Smith, H.B., Walraven, G., Bariau, E.M., et al. (2006) Long-Term Impact of Malaria Chemoprophylaxis on Cognitive Abilities and Educational Attainment: Follow-Up of a Controlled Trial. PLOS Clinical Trials, 1, e19. https://doi.org/10.1371/journal.pctr.0010019
[10]
Clarke, S.E., Jukes, M.C., Njagi, J.K., Khasakhala, L., Cundill, B., Otido, J., et al. (2008) Effect of Intermittent Preventive Treatment of Malaria on Health and Education in Schoolchildren: A Cluster-Randomised, Double-Blind, Placebo-Controlled Trial. The Lancet, 372, 127-138. https://doi.org/10.1016/S0140-6736(08)61034-X
[11]
Cunningham, J., Jones, S., Gatton, M.L., Barnwell, J.W., Cheng, Q., Chiodini, P.L., et al. (2019) A Review of the WHO Malaria Rapid Diagnostic Test Product Testing Programme (2008-2018): Performance, Procurement and Policy. Malaria Journal, 18, 387. https://doi.org/10.1186/s12936-019-3028-z
[12]
American Academy of Family Physicians (2015) Learning Matters: How Education Affects Health. https://www.aafp.org/news/blogs/leadervoices/entry/learning_matters_how_education _affects.html
[13]
Wogu, M. (2014) Prevalence of Malaria Parasite Infection among Pregnant Women Attending Antenatal Clinics in Port Harcourt, Rivers State, Nigeria. International Journal of Tropical Disease and Health, 3, 126-132. https://doi.org/10.9734/IJTDH/2013/2738
[14]
Inah, S.A., Ejemot-Nwadiaro, R., Inah, J.A. and Eko, J.E. (2017) Prevalence of Malaria among Pregnant Women and Children under Five Years in Abi Local Government Area, Cross River State, Nigeria. Asian Journal of Medicine and Health, 7, 1-7. https://doi.org/10.9734/AJMAH/2017/35911
[15]
Nnah, E.W. and Kasso, T. (2017) The Prevalence of Malaria and Helminth Infection in Pregnancy at Booking and Their Relationship to Anaemia at the University of Port Harcourt Teaching Hospital. International Journal of Tropical Disease and Hygiene, 28, 1-9.
[16]
Azikiwe, C.C.A., Ifezulike, C.C., Siminialayi, I.M., Amazu, L.U., Enye, J.C. and Nwakwunite, O.E. (2012) A Comparative Laboratory Diagnosis of Malaria: Microscopy versus Rapid Diagnostic Test Kits. Asian Pacific Journal of Tropical Biomedicine, 2, 307-310. https://doi.org/10.1016/S2221-1691(12)60029-X
[17]
Metoh, T.N., Fru, C.T., FonGah, P. and Zhoul, X. (2020) A Comparative Assessment of Rapid Diagnosis Test (RDT) versus Microscopy for Malaria Diagnosis in Health Care Facilities. Version 1. https://doi.org/10.21203/rs.2.20202/v1
[18]
Dalrymple, U., Arambepola, R., Gething, P.W. and Cameron, E. (2018) How Long Do Rapid Diagnostic Tests Remain Positive after Anti-Malarial Treatment? Malaria Journal, 17, 228. https://doi.org/10.1186/s12936-018-2371-9
[19]
Rapid Diagnostic Tests: How They Work. CDC. https://www.cdc.gov/malaria/malaria_worldwide/reduction/dx_rdt.html
[20]
Wongsrichanalai, C., Barcus, M.J., Muth, S., Sutamihardja, A. and Wernsdorfer, W.H. (2007) A Review of Malaria Diagnostic Tools: Microscopy and Rapid Diagnostic Test (RDT). In: Breman, J.G., Alilio, M.S. and White, N.J., Eds., Defining and Defeating the Intolerable Burden of Malaria III: Progress and Perspectives: Supplement to Volume 77(6) of American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, Northbrook, 119-127. https://www.ncbi.nlm.nih.gov/books/NBK1695
