A 50-year-old man had noticed the gradual appearance of asymptomatic skin lesions on the dorsal aspects of the hands during the last 3 years. Physical examination revealed clusters of multiple purplish dome-shaped infiltrated papules. Histopathological examination was compatible mutinucleate cell angiohistiocytoma. We treated him with 10,464 nm Nd:YAG laser, after the second session, some of the lesions had disappeared completely while the rest has gained substantial improvement. There were no adverse reactions and no recurrence after two years of follow-up. MCAH is a rare vascular fibrohistiocytic proliferation. No standard of care exists. We believe that Nd:YAG laser should be considered the treatment of choice.
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