Introduction: Simultaneous exposure to certain chemical agents and noise may cause synergistic, additive or potentiating effects on the auditory and vestibular system. However, there is still a lack of studies investigating simultaneous exposure to pesticides and noise in the vestibular system. Purpose: To analyze the findings of the vestibular evaluation of endemic diseases combat agents when simultaneously exposed to pesticides and noise. Method: Thirty-three male pesticide-exposed and noise-fighting endemic diseases combat agents participated in the study. The age range was 48 to 67 years (mean = 56 years). All participants underwent vestibular examinations, such as positional nystagmus research, spontaneous nystagmus with open and closed eyes, semi-spontaneous nystagmus, optokinetic nystagmus, pendular screening, per rotatory, caloric tests and tonal audiometry. Data were analyzed by descriptive statistics. Results: Altered exams were presented in 36.4% of the cases. There was no statistically significant relationship between pesticide handling time and test results (p = 0.2825). The results of pure tone audiometry correlated significantly (p = 0.0494) with the vestibular exams, as participants who presented with worse hearing thresholds at the frequency of 4000 Hz in the right ear also presented altered results in the vestibular exam. Conclusion: The present study concluded that more than 1/3 of the studied population presented with vestibular dysfunction, which was related to anterior and posterior labyrinth alteration (Cochlear-Vestibular Syndrome). No central vestibular alteration was noted in this population.
References
[1]
Carneiro, F.F., Rigotto, R.M., Augusto, L.G.S., Friedrich, K. and Búrigo, A.C. (Orgs) (2015) Dossiê ABRASCO: Um alerta sobre os impactos dos agrotóxicos na saúde. Escola Politécnica de Saúde Joaquim Venancio, Expressao Popular, Rio de Janeiro, Sao Paulo.
[2]
Torres, R. (2009) Agente de combate a endemias. Revista Poli-Saúde, Educacao e Trabalho, 3, 16-17.
[3]
Lima, E.P., Lopes, S.M.B., Amorin, M.I.M., Araújo, L.H.S., Neves, K.T. and Maia, E.R. (2009) Pesticide Exposure and Its Repercussion in the Health of Sanitary Agents in the State of Ceará, Brazil. Ciência & Saúde Coletiva, 14, 2221-2230.
https://doi.org/10.1590/S1413-81232009000600031
[4]
Occupational Safety and Health Administration (2018) OSHA News Releases 2018.
https://www.osha.gov/news/newsreleases/infodate-y/2018
[5]
Morata, T.C. and Little, M.B. (2002) Suggested Guidelines for Studying the Combined Effects of Occupational Exposure to Noise and Chemicals on Hearing. Noise & Health, 4, 73-87.
[6]
Buchanan, L.H. (2002) Auditory Effects of Occupational/Environmental Lead Exposure. In: Best Practices Workshop: Combined Effects of Chemicals and Noise on Hearing, National Institute for Occupational Safety and Health and the National Hearing Conservation Association, Cincinnati, 21-22.
[7]
Johnson, A.C. and Morata, T.C. (2010) Occupational Exposure to Chemicals and Hearing Impairment. In: Torén, K., Eds., Arbet och Halsa, Vol. 44, University of Gothenburg, Gothenburg, 110.
[8]
Campo, P., Morata, T.C. and Hong, O. (2013) Chemical Exposure and Hearing Loss. Disease-a-Month, 59, 119-138.
https://doi.org/10.1016/j.disamonth.2013.01.003
[9]
Morata, T.C. and Lacerda, A.B.M. (2013) Saúde auditiva. In: Zeigelboim, B.S. and Jurkiewicz, A.L., Eds., Multidisciplinaridade na Otoneurologia, Roca, Sao Paulo, 386-399.
[10]
SESA/PR (2013) Protocolo de avaliacao das intoxicacoes cronicas por agrotóxicos, Superintendência de Vigilancia em Saúde, Curitiba.
http://www.abrasco.org.br/UserFiles/Image/PDF%20protocolo%20avaliacao%20intoxicacao %20agrotoxico.pdf
[11]
Alcarás, P.A.S., Lacerda, A.B.M. and Marques, J.M. (2013) Estudo das emissoes otoacústicas evocadas e efeito de supressao em trabalhadores expostos a agrotóxicos e ruído. CoDAS, 25, 527-533.
[12]
Lacerda, A.B.M., Lobato, D. and Alcarás, P.A.S. (2019) Avaliacao audiológica para trabalhadores expostos a agentes químicos com ênfase nos pesticidas. In: Lopes, A.C., Goncalves, C.G.O. and Andrade, W.T., Eds., Fonoaudiologia e saúde auditiva do trabalhador, Book Toy, Ribeirao Preto, 133-157.
[13]
Ferreira Júnior, A.R., Torres, A.R.A. and Silva, C.M.A. (2015) Condicoes laborais dos agentes de combate a endemias e seus efeitos à saúde. Essencial Sobral, 16, 77-95.
[14]
Delgado, I.F. and Paumgartten, F.J.R. (2004) Intoxicacao e uso de pesticidas por agricultores do Município de Paty do Alferes, Rio de Janeiro, Brasil. Cadernos de Saúde Pública, 20, 180-186. https://doi.org/10.1590/S0102-311X2004000100034
[15]
Hoshino, A.C.H., Pacheco-Ferreira, H., Taguchi, C.K., Tomita, S. and Miranda, M.F. (2008) Ototoxicity Study in Workers Exposed to Organophosphate. Revista Brasileira de Otorrinolaringologia, 74, 912-918.
https://doi.org/10.1590/S0034-72992008000600015
[16]
Korbes, D., Silveira, A.F., Hyppolito, M.A. and Munaro, G. (2010) Alteracoes no sistema vestibulococlear decorrentes da exposicao ao agrotóxico: Uma revisao de literatura. Revista da Sociedade Brasileira de Fonoaudiologia, 15, 146-152.
https://doi.org/10.1590/S1516-80342010000100024
[17]
Guida, H.L., Morini, R.G. and Cardoso, A.C. (2010) Audiological Evaluation in Workers Exposed to Noise and Pesticide. Brazilian Journal of Otorhinolaryngology, 76, 423-427. https://doi.org/10.1590/S1808-86942010000400003
[18]
Jayasingue, S.S. and Pathirana, K.D. (2011) Effect of Deliberate Ingestion of Organophosphate or Paraquat on Brain Stem Auditory-Evoked Potential. Journal of Medical Toxicology, 7, 277-280. https://doi.org/10.1007/s13181-011-0173-3
[19]
Delecrode, C.R., Freitas, T.D., Frizzo, A.C.F. and Cardoso, A.C.V. (2012) Prevalence of Tinnitus in Workers Exposed to Noise and Organophosphate. International Archives of Otorhinolaryngologyl, 16, 328-334.
https://doi.org/10.7162/S1809-97772012000300005
[20]
Kós, M.I., Hoshino, A.C., Asmus, C.I.F., Mendonca, R. and Meyer, A. (2013) Efeitos da exposiao a agrotóxicos sobre o sistema auditivo periférico e central: Uma revisao sistemática. Cadernos de Saúde Pública, 29, 1491-1506.
https://doi.org/10.1590/S0102-311X2013001200003
[21]
Gatto, M.P., Fioretti, M., Fabrizi, G., Gherardi, M., Strafella, E. and Santarelli, L. (2014) Effects of Potential Neurotoxic Pesticides on Hearing Loss: A Review. NeuroToxicology, 42, 24-32. https://doi.org/10.1016/j.neuro.2014.03.009
[22]
Judai, M.A. (2015) Estudo dos limiares auditivos em frequências convencionais e altas frequências de moradores e trabalhadores expostos a praguicidas na regiao do Pontal do Paranapanema. Ph.D. Dissertation, Universidade do Oeste Paulista, Presidente Prudente.
[23]
Lobato, D.C.B. (2015) Disfuncao auditiva induzida por agrotóxicos em trabalhadores agrícolas do Paraná. Ph.D. Thesis, Universidade Tuiuti do Paraná, Curitiba.
[24]
Tomiazzi, J.S. (2017) Avaliacao auditiva e citogenética de trabalhadores rurais do Pontal do Paranapanema—SP expostos a agroquímicos e tabagismo, isolado ou combinado. Ph.D. Dissertation, Universidade do Oeste Paulista, Presidente Prudente.
[25]
Sena, T.R.R., Dourado, S.S.F., Lima, L.V. and Antoniolli, A.R. (2018) The Hearing of Rural Workers Exposed to Noise and Pesticides. Noise Health, 20, 23-26.
[26]
Dick, R.B., Steenland, K., Krieg Jr., E.F. and Hines, C.J. (2001) Evaluation of Acute Sensory-Motor Effetcs and Test Sensitivity Using Termiticide Workers Exposed to Chlorpyrifos. Neurotoxicology and Teratology, 23, 381-393.
https://doi.org/10.1016/S0892-0362(01)00143-X
[27]
Cogo, L.A., Murashima, A.A.B., Santos Filha, V.A.V., Hyppolito, M.A. and Silveira, A.F. (2014) Avaliacao funcional do sistema vestibular de cobaias intoxicadas por meio da prova calórica. Revista CEFAC, 16, 1434-1442.
https://doi.org/10.1590/1982-021620149313
[28]
Cogo, L.A., Santos Filha, V.A.V., Murashima, A.A.B., Hyppolito, M.A. and Silveira, A.F. (2016) Morphological Analysis of the Vestibular System of Guinea Pigs Poisoned by Organophosphate. Brazilian Journal of Otorhinolaryngology, 82, 11-16.
https://doi.org/10.1016/j.bjorl.2015.10.001
[29]
Mangabeira-Albernaz, P.L., Gananca, M.M. and Pontes, P.A.L. (1976) Operational Model of the Vestibular Apparatus. In: Mangabeira-Albernaz, P.L. and Gananca, M.M. Ed., Vertigem, Moderna, Sao Paulo, 29-36.
[30]
Costa, K.C.F., Silva, S.M.R. and Gananca, C.F. (2005) Study of Oculomotor and Vestibular Tests Using Digital Vectonystagmography. Disturb. Comun, 17, 315-322.
[31]
Palatas, O.H.G., Gananca, C.F. and Gananca, F.F. (2009) Quality of Life of Individuals Submitted to Vestibular Rehabilitation. Brazilian Journal of Otorhinolaryngology, 75, 387-394. https://doi.org/10.1590/S1808-86942009000300014
[32]
Arlien-Soborg, P., Zilstorff, K., Grandjean, B. and Pedersen, L.M. (1981) Vestibular Dysfunction in Occupational Chronic Solvent Intoxication. Clinical Otolaryngology & Allied Sciences, 6, 285-290. https://doi.org/10.1111/j.1365-2273.1981.tb01549.x
[33]
Manjabosco, C.W., Morata, T.C. and Marques, J.M. (2004) Perfil Audiométrico de trabalhadores agrícolas. Arquivos Internacionais de Otorrinolaringologia, 8, 285-295.
[34]
Sunwook, K., Nussbaum, M.A., Quandt, S.A., Laurienti, P.J. and Arcury, T.A. (2016) Effects of Lifetime Occupational Pesticide Exposure on Postural Control among Farmworkers and Non-Farmworkers. Journal of Occupational and Environmental Medicine, 58, 133-139. https://doi.org/10.1097/JOM.0000000000000655
[35]
Zanardini, F.H., Zeigelboim, B.S., Jurkiewics, A.L., Marques, J.M. and Martins-Bassetto, J. (2007) Reabilitacao vestibular em idosos com tontura. Pró-Fono Revista de Atualizacao Científica, 19, 177-184. https://doi.org/10.1590/S0104-56872007000200006
[36]
Kamel, F., Rowland, A.S., Park, L.P., Anger, W.K., Baird, D.D., Gladen, B.C., Moreno, T., Stallone, L. and Sandler, D.P. (2003) Neurobehavioral Performance and Work Experience in Florida Farmworkers. Environmental Health Perspectives, 111, 1765-1772. https://doi.org/10.1289/ehp.6341
[37]
Tavares, F.S., Santos, M.F.C. and Knobel, K.A.B. (2008) Reabilitacao vestibular em um hospital universitário. Revista Brasileira de Otorrinolaringologia, 74, 241-247.
https://doi.org/10.1590/S0034-72992008000200014
[38]
Zeigelboim, B.S., Klagenberg, K.F., Rosa, M.R.D., Paulin, F., Jurkiewicz, A.L. and Marques, J.M. (2008) Achados vestibulares na populacao idosa. Fisioterapia em Movimento, 21, 89-99.
[39]
Lourenco, E.A., Lopes, K.C., Pontes-JR, A., Oliveira, M.H., Umemura, A. and Vargas, A.L. (2005) Distribution of Neurotological Findings in Patients with Cochleovestibular Dysfunction. Brazilian Journal of Otorhinolaryngology, 71, 288-296.
https://doi.org/10.1016/S1808-8694(15)31325-2