9,9-二(3-氨基-4-羟基苯基)?愣值暮铣捎氡碚?
The Synthesis and Characterization of 9,9-Bis(3-Anino-4-HydroxyPhenyl)Xanthene

将9，9-二（4-羟基苯基）?愣钟胫柿颗ǘ任?20；的稀硝酸在10~15℃下发生硝化反应约3 h，以86.5；的产率合成了中间体9，9-二（3-硝基-4-羟基苯基）?愣郑?然后以10；的 Pd/ C 和甲醇为催化剂/溶剂体系，采用加氢还原方法，在75~80℃将中间体还原得到9，9-二（3-氨基-4-羟基苯基）?愣郑?产率为92.7；，2步反应总收率为80.2；，并用1 H NMR、IR 和元素分析等方法证实了上述2种化合物的结构.
Nitration between 9,9-bis(4-hydroxyphenyl)xanthene(1)with 20； aqueous HNO3 15 ~ 20 ℃ for 3 h yielded 9,9-bis(3-nitro-4-hydroxyphenyl)xanthene(2)in 86. 5； yield,which was further converted to 9,9-bis(3-amino-4-hydroxyphenyl)xanthene(3)in 92. 7； yield by reduction with hydrogen in the presence of catalytic amount of Pd / C at 75 ~ 80 ℃ for 1 h in methanol solvent. The two-step overall yield of 3 was about 80. 2；(based on compound 1)and their structures of 2 and 3 were characterized by 1 H NMR,IR and elemental analysis tech-nique