多壁碳纳米管-石墨烯复合膜修饰电极电化学检测异烟肼
The Electrochemical Detection of Isoniazid on a MWCNT/Graphene Composite Film Modified Electrode

采用水合肼还原法制备了多壁碳纳米管（MWCNT）-石墨烯（GR）纳米复合物（MWCNT-GR），并采用滴涂法制备了此纳米复合物修饰的玻碳电极（MWCNT-GR/ GCE），研究了该修饰电极上异烟肼（Isonia-zid，INZ）的电化学行为.结果表明：在 pH 值为4.0的 HAc-NaAc 缓冲溶液中，异烟肼在0.35 V 处产生一灵敏的不可逆氧化峰.线性扫描伏安法测定异烟肼的线性范围为1.0×10-7~1.0×10-4 mol？L -1，检出限为5.0×10-8 mol？L -1（S/ N =3）.用该法测定了异烟肼注射液中异烟肼的含量，结果令人满意.
The multi-walled carbon nanotube / graphene composite(MWCNT-GR)were synthesized by using hydra-zine as a reduction agent. Based on this,a MWCNT-GR composite film modified glass carbon electrode(MWCNT-GR/ GCE)was fabricated. The electrochemical behavior of isoniazid(INZ)on this modified electrode was investi-gated carefully. The results showed that an irreversible oxidation peak at 0. 35 V of ING was observed on cyclic vol-tammograms in HAc-NaAc buffer solution(pH 4. 0). The linear range for determination of INZ by LSV was 1. 0 × 10 - 7 ~ 1. 0 × 10 - 4 mol？L - 1 with the detection limit of 5. 0 × 10 - 8 mol？L - 1(S / N = 3). Finally,this method was successfully employed to determine isoniazid in injection