聚L-组氨酸/石墨烯复合膜修饰电极对多巴胺和尿酸的同时测定
Simultaneous Determination of Dopamine and Uric Acid on Poly-(L-His)/ERGO Modified Glassy Carbon Electrode

采用循环伏安法制备了聚L-组氨酸/石墨烯复合膜修饰电极(poly-(L-His)/ERGO/GCE),研究了抗坏血酸(AA)、多巴胺(DA)和尿酸(UA)在该修饰电极上的电化学性质.研究结果表明:AA、DA和UA在该修饰电极上具有良好的电化学响应,且这3种物质的氧化峰能完全分离.据此建立了在大量AA存在下同时测定DA和UA的新方法,微分脉冲伏安法测定DA和UA的线性范围分别为3.0×10-7～3.0×10-5 mol？L-1和5.0×10-7～3.0×10-5 mol？L-1,检出限分别为3.0×10-7和5.0×10-7 mol？L-1.
A poly-(L-His)/ERGO hybrid film modifying electrode had been fabricated by using cyclic voltammommetry.The electrochemical behaviors of dopamine(DA),uric acid(UA)and ascorbic acid(AA)were investigated.The results showed that the resulting modified electrode exhibited excellent electrocatalytic activity toward the electrooxidation of DA and UA and had superior selectivity for the determination of DA,UA in the presence of mass AA.Under the optimum conditions,the liner calibration curves of 3.0×10～3.0×10mol？L and 5.0×10～3.0×10mol？L with the detection is 3.0×10 mol？L and 3.0×10mol？L were obtained for DA and UA,respectively