摘要 目的 探讨成人原发性腹膜后畸胎瘤的临床特点、治疗方法及预后。 方法 回顾性分析我院2001年1月—2018年9月收治的50例成年腹膜后畸胎瘤病人的临床资料及治疗、随访结果，并分析影响肿瘤复发的相关因素。 结果 50例病人中男10例，女40例；良性病变49例，恶性病变1例。所有病人均行手术治疗，7例病人术后复发。对影响腹膜后畸胎瘤复发的单因素分析结果显示，病人年龄、肿瘤是否残留与术后复发有关（χ2=5.05，P<0.05,P=0.002）；进一步行多因素Logistic回归分析显示，肿瘤是否残留与术后复发显著相关（OR=13.320，95%CI=0.003～0.414，P<0.05）。 结论 成人腹膜后畸胎瘤良性多见，主要治疗方式为手术治疗，术前应根据肿瘤的位置及大小选择合适的手术入路，力求完整切除肿瘤，避免复发。无论肿瘤是否良恶性，术后均应定期复查，以尽早发现肿瘤复发或恶变情况，并及时治疗。 Abstract：Objective To investigate the clinical features, treatment methods, and prognosis of primary retroperitoneal teratoma in adults. Methods A retrospective analysis was performed for the clinical data, treatment, and follow-up data of 50 adult patients with retroperitoneal teratoma who were admitted to our hospital from January 2001 to September 2018, and the influencing factors for tumor recurrence were analyzed. Results There were 10 male and 40 female patients, and of all patients, 49 had benign lesions and 1 had malignant lesion. All patients underwent surgical treatment and 7 patients experienced recurrence after surgery. The univariate analysis of the influencing factors for the recurrence of retroperitoneal teratoma showed that age and presence or absence of tumor residue were associated with postoperative recurrence (χ2=5.05,P<0.05,P=0.002), and further multivariate Logistic regression analysis showed that presence or absence of tumor residue was significantly associated with postoperative recurrence (OR=13.320,95%CI=0.003-0.414,P<0.05). Conclusion Retroperitoneal teratoma in adults is often benign. Surgical treatment is the main treatment method, and appropriate surgical approach should be selected according to tumor location and size before surgery, in order to achieve complete resection of tumor and avoid recurrence. No matter whether the tumor is benign or malignant, regular reexamination should be performed after surgery to identify recurrence or malignant transformation of tumor as soon as possible and give timely treatment
