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- 2018
Poly (Ethylene-Co-Vinyl Acetate) Blends for Controlled Drug ReleaseDOI: 10.21767/2321-547X.1000025 Keywords: Drug release, Polymer blends, Polyvinyl acetate polymer, Ethylene vinyl acetate copolymer, Paracetamol, list of open access journals, open access, open access journals, open access publication, open access publisher, open access publishing, open access journal articles, imedpub, imedpub publishing, insight medical publishing, imedpub online Abstract: Ethylene vinyl acetate copolymer (EVA) was blended with polyvinyl acetate polymer (PVAc) to form EVA/PVAc blends. Paracetamol was used as a drug model in the investigated blends. Different weight ratios of the two polymers in the blend were investigated, these are (100/0, 80/20 50/50, 20/80, 0/100 w/w EVA/PVAc). The concentration of the drug was kept constant. The micro structure, as well as crystallinity and chemical composition of these blends were investigated. The scanning electron microscopy (SEM) has been conducted for blends before and after release. Crystallization behavior of EVA was investigated as well as X-ray diffraction (XRD) of the blends. Besides FTIR spectrum of the samples and equilibrium swelling and deswelling of the blends has been carried out
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