Feasibility study of large breast benign masses excision with ultrasoundguided Mammotome VABB system

Background: This study aimed to investigate the feasibility of large breast benign masses excision with ultrasound-guided Mammotome minimally invasive surgery. Materials and Methods: The clinical data of 1023 patients with breast benign masses in our hospital from December 2013 to December 2015 were collected and analysed. Patients were divided into experimental group with 302 cases (d>2.5 cm) and control group with 721 cases (d ≤ 2.5 cm). All the patients received Mammotome excision, and the treatment effects were followed up. The resection rate, complications and cosmetic effect were compared between the two groups. Results: All lesions in the two groups were confirmed as benign masses, and the detection rate of residual cancer cells in surgical resection margins was all below 5%, indicating the complete resection rate in two groups was all higher than 95%. No significant difference between the two groups was found in terms of the resection rate. The complication morbidity of pain, hematoma, skin ecchymosis and active bleeding in the experimental group were higher than that in the control group, and the difference was statistically significant (p<0.05). The short-term cosmetic effect was better in the control group than that of the experimental group, and the difference was significant (p=0.029). No significant differences of the long-term cosmetic effect and the subjective evaluation (6 months after the operation) between the two groups were found. Conclusions: The Mammotome excision of large breast benign masses had many advantages, such as safety, minimally invasive, cosmetic and satisfaction in resection rate, which made the surgical procedure feasible and worth to be recommended