Sinister presentation of a neglected case of late onset hemorrhagic disease of newborn.

Introduction: Hemorrhagic disease of newborn is an important cause of bleeding in an infant. Late hemorrhagic disease of newborn occurs after seventh day of life. Case description: We report the case of a 2 month old infant who presented initially with unilateral subperiosteal hemorrhage of cheek and following which he developed life threatening intracerebral hemorrhage. Management with vitamin K supplementation, fresh frozen plasma transfusion and neuroprotective ventilation strategy with effective seizure control proved to be successful. Discussion: Vitamin K deficiency plays the key role by altering the prothrombin time and activated partial thromboplastin time. Among the types of intracranial bleeding in late hemorrhagic disease of newborn, intracerebral parenchymal bleeding is least common. Conclusion: Timely diagnosis of a case of late hemorrhagic disease of newborn is very crucial in preventing mortality and morbidity