Glucose mediated solvent free synthesis of some N-(2-oxoindolin-3-ylidene)- benzohydrazide derivatives and their antimicrobial activity

A simple, efficient and green methodology has been developed for the synthesis of N-(2-oxoindolin-3- ylidene)benzohydrazide derivatives using D-glucose as catalyst. All the compounds were synthesized under solid phase synthesis by simple physical grinding of reactants. All the synthesized compounds were evaluated for their antimicrobial activity, where compounds 3(d-f) shown moderate activity and others with none