The effect of aerobic intermittent training on resting level of serum vascular cell adhesion molecules in sedentary young woman

Cardiovascular diseases in particular atherosclerosis are among main causes of disability and fatality in the world. There is a great deal of evidence suggesting that vascular adhesion molecules is one of the new inflammatory factors prognostic of cardiovascular disease, particularly atherosclerosis. This research aims to explore the impact of intermittent exercise on serum concentration of vascular cell adhesion molecules-1 (VCAM-1) in sedentary young woman. For this purpose, 30 female overweight volunteer students (BMI ≥ 26) of Azad University Shahre Qods Campus were selected and randomly divided into two groups: intermittent training group and control group. Training groups exercised for 12 weeks, three sessions a week with definite intensity and distance. VCAM, body weight, fat percentage, BMI And maximum oxygen consumption were measured both before and after the 12-week exercise. Using Independent T-test, the results showed that interval training had significant effect on VCAM, body weight, fat percentage, BMI and maximum oxygen consumption (p ≤ 0.05). Our findings showed that with significant reduction of adhesion molecules levels and decreasing inflammation intermittent exercise may perhaps play an effective role in prevention, control and mitigation of atherosclerosis