Natural Remedies Target Different Therapeutic Pathways in Oral Mucositis Induced by Cancer Chemo or Radiotherapy

Oral mucositis is an inflammatory condition that affects mucosa of the oral cavity. The etiology of this type of inflammation is associated with exposure to radiotherapy or chemotherapeutic drugs [1,2]. Patients under chemotherapeutic protocols that are associated with bone marrow-suppression are at high risk of oral mucositis. Approximately 60-100% of those patients may encounter oral mucositis, patients who need radiotherapy directed at the oral, sub mandibular and pharyngeal area such as those who have squamous cell carcinoma in the head and neck region commonly have oral mucositis [3]. Combination of radiotherapy and chemotherapy is associated with a risk of around 100% [2]. Oral mucositis is a painful condition that significantly affects patients’ quality of life [4]. The sever cases is associated with ulcerated mucosa and secondary infection which may led to life-threatening sepsis