OXIDATIVE STRESS UNDER INTENSE PHYSICAL EXERTION IN HUMANS AND ANIMALS

Sa？etak Oxidative stress indicates an imbalance in the body between pro-oxidant and antioxidant in favor of a pro-oxidant. To shift the balance may occur if the reduced antioxidant defense of the body or if the increased production of free radicals. Antioxidants are those substances that in a small amount in a short time can neutralize free radicals and other oxidants. They are produced in the cell or organism in food intake or in the form of dietary antioxidants in food or liquid to drink. Antioxidants prevent the formation of free radicals in the body, destroying free radicals created or repair damage in cells caused the action of free radicals. Paper showed biomarkers of oxidative stress in humans and animals, divided to enzymatic, non-enzymatic and other. Biomarkers of peripheral muscle fatigue in humans and animals are markers of cellular muscle damage and muscle stress indicators, and are used for insight into the mechanisms of fatigue during exercise to detect increased fatigue or found deficient metabolic pathways. The determination of oxidative stress is important because of the possibility of timely inclusion of antioxidant substances that increase the antioxidant capacity of human and animal organism