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Cirrhotic Patients Undergoing Cardiac Surgery: Why Not to Develop a More Specific Heart-Liver Score?

DOI: 10.4236/wjcs.2021.111001, PP. 1-7

Keywords: Liver Cirrhosis, Cardiac Surgery, Risk Score

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Abstract:

Despite not included in the traditional risk scores before surgery, liver cirrhosis, especially in advanced stages, has always influenced strongly final outcome both on short and midterm in patients undergoing cardiac surgery. Growing incidence of non-alcoholic fatty liver disease interlinked with metabolic syndrome and significant advancements in medical therapy have actually increased the likelihood of cardiac surgery in cirrhotic patients. To date, Child-Pugh and MELD scores have been commonly used to predict mortality and postoperative hepatic decompensation, but on the other hand, both traditional risk scores show some limitations for evaluation of hepatopathic patients undergoing specifically cardiac surgery. In this context, a specific Heart-Liver score hasn’t been developed yet in the attempt to outline a patient profile able to face surgery, therefore addressing us to adopt the best strategy possible for each case. If CP class A or low MELD score (<11) patients tolerate cardiac surgery with a mild increase in mortality and morbidity, currently state of art recommends particular caution towards surgery idea in presence of advanced hepatic disease. As far as cardiac surgery represents the unique therapeutic strategy in several life-threatening cases, anyway surgical correction of cardiac pathology won’t guarantee an increased life expectancy in accordance with the persistent liver dysfunction. Hereby, this paper will focus on preoperative parameters that should be considered in the future realization of a Heart-Liver prognostic score for overcoming limitations and difficulties related to the impact of liver disease on final clinical outcome.

References

[1]  Hawkins, R.B., Young, B.A.C., Mehaffey, J.H., Speir, A.M., Quader, M.A., Rich, J.B. and Ailawadi, G. (2019) Model for End-Stage Liver Disease Score Independently Predicts Mortality in Cardiac Surgery. The Annals of Thoracic Surgery, 107, 1713-1719.
https://doi.org/10.1016/j.athoracsur.2018.12.011
[2]  Filsoufi, F., Salzberg, S.P., Rahmanian, P.B., Schiano, T.D., Elsiesy, H., Squire, A. and Adams, D.H. (2007) Early and Late Outcome of Cardiac Surgery in Patients with Liver Cirrhosis. Liver Transplantation, 13, 990-995.
https://doi.org/10.1002/lt.21075
[3]  Weis, F., Kilger, E., Beiras-Fernandez, A., Hinske, C.L., Nassau, K., Adnan, L., Vicol, C., Kur, F. and Mohnle, P. (2014) Indocyanine Green Clearance as an Outcome Prediction Tool in Cardiac Surgery: A Prospective Study. Journal of Critical Care, 29, 224-229.
https://doi.org/10.1016/j.jcrc.2013.10.023
[4]  Lisotti, A., Azzaroli, F., Buonfiglioli, F., Montagnani, M., Cecinato, P., Turco, L., Calvanese, C., Simoni, P., Guardigli, M., Arena, R., Cucchetti, A., Colecchia, A., Festi, D., Golfieri, R. and Mazzella, G. (2014) Indocyanine Green Retention Test as a Noninvasive Marker of Portal Hypertension and Esophageal Varices in Compensated Liver Cirrhosis. Hepatology, 59, 643-650.
https://doi.org/10.1002/hep.26700
[5]  Araujo, L., Dombrovskiy, V., Kamran, W., Lemaire, A., Chiricolo, A., Lee, L.Y. and Lemaire, A. (2017) The Effect of Preoperative Liver Dysfunction on Cardiac Surgery Outcomes. Journal of Cardiothoracic Surgery, 12, 73.
https://doi.org/10.1186/s13019-017-0636-y
[6]  Chou, H.W., Lin, M.H., Chen, Y.S. and Yu, H.Y. (2020) Impact of MELD Score and Cardiopulmonary Bypass Duration on Post-Operative Hypoxic Hepatitis in Patients with Liver Cirrhosis Undergoing Open Heart Surgery. Journal of the Formosan Medical Association, 119, 838-844.
https://doi.org/10.1016/j.jfma.2019.08.028
[7]  Xavier, S., Norris, C.M., Ewasiuk, A., Kutsogiannis, D.J., Bagshaw, S.M., van Diepen, S., Townsend, D.R., Negendran, J. and Karvellas, C.J. (2020) The Impact of Cirrhosis in Patients Undergoing Cardiac Surgery: A Retrospective Observational Cohort Study. Canadian Journal of Anesthesia, 67, 22-31.
https://doi.org/10.1007/s12630-019-01493-7

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