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New Hemisynthetic Oleanane Saponin with Antimicrobial Activities

DOI: 10.4236/abc.2021.111001, PP. 1-11

Keywords: Saponin, Acetylation, Methylation, Antimicrobial Activities

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Abstract:

A new hemisynthetic oleanane saponin: 4',2\",3\",4\",6\"-penta-O-acetyl-6'-O- methyl-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucuronopyranosyl oleanolic acid (2) was obtained after acetylation and methylation reaction on 3-O-β-D- glucopyranosyl-(1→2)-β-D-glucuronopyranosyl oleanolic acid (1). Its structure

References

[1]  Van Dyck, S., Flammang, P., Meriaux, C., Bonnel, D., Salzet, M. and Fournier, I. (2010) Localization of Secondary Metabolites in Marine Invertebrates: Contribution of MALDI MSI for the Study of Saponins in Cuvierian Tubules of Holothuria forskali. PLoS ONE, 5, e13923.
https://doi.org/10.1371/journal.pone.0013923
[2]  Hostettmann, K.A. and Marston, A. (1995) Saponins. Cambridge University Press, Cambridge, 548.
https://doi.org/10.1017/CBO9780511565113
[3]  Price, K.R., Johnson, I.T. and Fenwick, G.R. (1987) The Chemistry and Biological Significance of Saponins in Food and Feeding Stuffs. Critical Reviews in Food Science and Nutrition, 26, 127-135.
https://doi.org/10.1080/10408398709527461
[4]  Zhang, S. and Hu, Z. (1985) Anti-Ulcerogenic Effects of Ginseng Flower Saponins in the Rat Zhongyao Tongbao 10: 331. Chemical Abstracts, 104, 512.
[5]  Okubo, K., Kudou, S., Uchida, T., Yoshiki, Y., Yoshikoshi, M. and Tonomura, M. (1994) Soybean Saponins and Isoflavonoids: Structure and Antiviral Activity against Human Immunodeficiency Virus in Vitro. In: Food Phytochemicals for Cancer Prevention I, ACS Symposium Series, Vol. 546, American Chemical Society, Washington DC, Chapter 26, 330-339.
https://doi.org/10.1021/bk-1994-0546.ch026
[6]  Just, M.J., Recsio, M.G., Gner, R.M., Cuellar, M.J., Marez, S., Bilia, A.R. and Rios, J. (1998) Anti-Inflammatory Activity of Unusual Lupane Saponins from Buleurum fruiticescens. Planta Medica, 64, 404-407.
https://doi.org/10.1055/s-2006-957469
[7]  Woldemichael, G.M. and Wink, M. (2001) Identification and Biological Activities of Triterpenoid Saponins from Chenopodium quinoa. Journal of Agricultural and Food Chemistry, 49, 2327-2332.
https://doi.org/10.1021/jf0013499
[8]  Sparg, S.G., Light, M.E. and Van, S.J. (2004) Biological Activities and Distribution of Plant Saponins. Journal of Ethnopharmacology, 94, 219-243.
https://doi.org/10.1016/j.jep.2004.05.016
[9]  Fouedjou, T.R., Teponno, R.B., Quassinti, L., Bramucci, M., Petrelli, D., Vitali, L.A., Fiorini, D., Tapondjou, A.L. and Barboni, L. (2014) Steroidal Saponins from the Leaves of Cordyline fruticosa (L.) A. Chev. and Their Cytotoxic and Antimicrobial Activity. Phytochemistry Letters, 7, 62-68.
https://doi.org/10.1016/j.phytol.2013.10.001
[10]  Tagousop, C.N., Tamokou, J.D.D., Kengne, C.I., Ngnokam, D. and Voutquenne-Nazabadioko, L. (2018) Antimicrobial Activities of Saponins from Melanthera elliptica and Their Synergistic Effects with Antibiotics against Pathogenic Phenotypes. Chemistry Central Journal, 12, 97.
https://doi.org/10.1186/s13065-018-0466-6
[11]  Deore, S.L., Khadabadi, S.S., Chittam, K.P., Bhujade, P.G., Wane, T.P., Nagpurkar, Y.R., Chanekar, P.D. and Jain, R.G. (2009) Properties and Pharmacological Applications of Saponins. Pharmacologyonline, 2, 61-84.
[12]  Wang, R.F., Li, J., Hu, H-J., Li, J., Yang, Y.-B., Yang, L. and Wang, Z.-T. (2016) Chemical Transformation and Target Preparation of Saponins in Stems and Leaves of Panax notoginseng. Journal of Ginseng Research, 1-7.
[13]  Penders, A. and Delaude, C. (1994) Triterpenoid Saponins from Melanthera scandens. Phytochemistry, 37, 821-825.
https://doi.org/10.1016/S0031-9422(00)90364-9
[14]  Clinical and Laboratory Standards Institute (1997) Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts. Approved Standard (CLSI Document M27-A), Clinical and Laboratory Standards Institute, Wayne.
[15]  Clinical and Laboratory Standards Institute (2009) Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard Eighth Edition (CLSI Document M07-A8). Clinical and Laboratory Standards Institute, Wayne.
[16]  Li, Y., Du, Y. and Zou, C. (2009) Effects of pH on Antioxidant and Antimicrobial Properties of Tea Saponins. European Food Research and Technology, 228, 1023-1028.
https://doi.org/10.1007/s00217-009-1014-3
[17]  Dourmashkin, R.R., Dougherty, R.M. and Harris, R.J.C. (1962) Electron Microscopic Observations on Rous sarcoma Virus and Cell Membranes. Nature, 194, 1116-1119.
https://doi.org/10.1038/1941116a0
[18]  Bangham, A.D. and Horne, R.W. (1962) Action of Saponin on Biological Cell Membranes. Nature, 196, 952-953.
https://doi.org/10.1038/196952a0
[19]  Glauert, A.M., Dingle, J.T. and Lucy, J.A. (1962) Action of Saponin on Biological Cell Membranes. Nature, 196, 953-955.
https://doi.org/10.1038/196953a0

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