Acute Generalized Peritonitis in Intensive Care Unit at University Hospital of Brazzaville, Republic of Congo: Etiological, Therapeutic Aspects and Issues
Aim: To
determine etiological, therapeutic aspects and issues of AGP in intensive care
unit (ICU) at University Hospital of Brazzaville (UHB). Materials and Methods: It was a retrospective and descriptive study carried out from January to
December 2016 in ICU at UHB. We collected completed medical records of patients
admitted and operated for AGP regardless of age or sex. The parameters studied
were age, sex, admission’s reasons, etiologies, management, post-operative
complications, length of hospital and mortality. Data were treated in Excel
2010 and Epi info 2007. Results: Thirty-one complete medical records
were identified (mean age: 40.6 ± 22.0 years). The sex ratio was 2.4. Shock was
the most common reason for admission with 67.7% of the cases. The etiologies of
AGP were dominated by gastroduodenal perforating ulcer (41.9%) followed by complicated appendicitis
(19.4%). The management of all patients was medico-surgical. The bi antibiotic
ceftriaxone-metronidazole was administered in 29 patients (93.6%). 18 patients
(59.1%) received vasopressor therapy. The complications had occurred among 9
patients i.e. 29% of the cases; parietal
suppurations represented 44.5% of the complications. The average length of
hospitalization was 5.2 ± 4.6 days. The overall mortality was 41.9%. Conclusion: In our study, the most frequent etiologies were gastroduodenal perforating
ulcer and complicated appendicitis. They affected young patients. The
complications were dominated by parietal suppurations. The mortality rate was
high.
References
[1]
Skipworth, R.J.E. and Fearon, K.C.H. (2008) Acute Abdomen: Peritonitis. Surgery (Oxford), 26, 98-101. https://doi.org/10.1016/j.mpsur.2008.01.004
[2]
Montravers, P., Allyn, J. and Olinca, A. (2011) Prise en charge des péritonites. Journal des Anti-infectieux, 13, 25-33. https://doi.org/10.1016/j.antinf.2011.01.003
[3]
Jovanovic, D., Loncar, Z., Doklestic, K. and Karamarkovic, A. (2015) Intra-Abdominal Infection and Acute Abdomen-Epidemiology, Diagnosis and General Principles of Surgical Management. Sanamed, 10, 69-78. https://doi.org/10.5937/sanamed1501069J
[4]
Mulari, K. and Leppäniemi, A. (2004) Severe Secondary Peritonitis Following Gastrointestinal Tract Perforation. Scandinavian Journal of Surgery, 93, 204-208. https://doi.org/10.1177/145749690409300306
[5]
Dieng, M., Ndiaye, A., Konaté, I., Ka, O., Cissé, M., Dia, A., et al. (2007) Etude des facteurs de morbidité et de mortalité des péritonites aiguës généralisées: à propos d’une série de 221 cas opérés. Journal Africain de chirurgie Digestive, 7, 679-685.
[6]
Montravers, P., Dupont, H., Leone, M., et al. (2015) Prise en charge des infections intra-abdominales. Anesthésie & Réanimation, 1, 75-99. https://doi.org/10.1016/j.anrea.2014.12.006
[7]
Hadley, G.P. (2014) Intra-Abdominal Sepsis—Epidemiology, Aetiology and Management. Seminars in Pediatric Surgery, 23, 357-362. https://doi.org/10.1053/j.sempedsurg.2014.06.008
[8]
Gaye, I., Leye, P.A., Traoré, M.M., Ndiaye, P.I., Ba, E.H.B., Bah, M.D., et al. (2016) Prise en charge péri opératoire des urgences chirurgicales abdominales chez l’adulte au CHU Aristide Le Dantec. The Pan African Medical Journal, 24, 190. http://www.panafrican-med-journal.com/content/article/24/190/full/ https://doi.org/10.11604/pamj.2016.24.190.9929
[9]
Azgaou, I., Benomar, R., Benelkhaiat and Finech, B. (2011) Profil épidémiologique, clinique et thérapeutique des péritonites aiguës: étude rétrospective sur 2 ans au CHU Mohamed VI de Marrakech.
[10]
Ngo Nonga, B., Mouafo Tambo, F.F., Ngowe Ngowe, M., Takongmo, S. and Sosso, M.A. (2010) Etiologies des péritonites aiguës généralisées au CHU de Yaoundé. Revue Africaine de Chirurgie et Spécialités, 4, 30-32. https://doi.org/10.4314/racs.v4i7.66378
[11]
Rakotomavo, F.A., Riel, A.M., Rakotoarison, R.C.N., Randrianambinina, H., Randrianambinina, T. and Randriamiarana, M. (2012) Péritonite aigüe: Aspects épidémio-clinique et étiologique dans un service des urgences chirurgicales malgache. A propos de 60 cas. Journal Africain d’Hépato-Gastroentérologie, 6, 33-37. https://doi.org/10.1007/s12157-011-0355-2
[12]
Coulibaly, B., Togola, B., Traoré, D., Coulibaly, M., Diallo, S., Sanogo, S., et al. (2013) Péritonites postopératoires dans le service de chirurgie B du CHU du Point G. Mali Medical, 28, 10-12.
[13]
Kassegne, I., Kanassoua, K.K., Sewa, E.V., Tchangai, B., Sambiani, D.M., Ayite, A.E., et al. (2016) Prise en charge des péritonites aiguës généralisées au Centre Hospitalier Universitaire de Kara. Revue Africaine d’Anesthésiologie et de Médecine d’Urgence, 18.
[14]
Harouna, Y.D., Abdou, I., Saidou, B. and Bazira, L. (2001) Les péritonites en milieu tropical: Particularités étiologiques et facteurs pronostiques actuels—A propos de 160 cas. Médecine d’Afrique Noire, 48, 103-106.
[15]
Mehinto, D.K., Gandaho, I., Adoukonou, O., Bagnan, O.K. and Padonou, N. (2010) Aspects épidémiologiques, diagnostiques et thérapeutiques des perforations du grêle d’origine typhique en chirurgie viscérale du Centre National Hospitalier et Universitaire-Hubert Koutoucou Maga de Cotonou. Médecine d’Afrique Noire, 57, 535-540.
[16]
Doklestić, S.K., Bajec, D.D., Djukić, R.V., Bumbaširević, V., Detanac, A.D., Detanac, S.D., et al. (2014) Secondary Peritonitis—Evaluation of 204 Cases and Literature Review. Journal of Medicine and Life, 7, 132-138.
[17]
Kambiré, J.L., Zaré, C., Sanou, B.G. and Kambou, T. (2017) étiologies et pronostic des péritonites secondaires au centre hospitalier universitaire de Bobo-Dioulasso (Burkina Faso). Journal Africain D’Hepato-Gastroenterologie, 11, 149-151. https://doi.org/10.1007/s12157-017-0719-3
[18]
Sanogo, Z.Z., Camara, M., Doubia, M.M., et al. (2012) Perforations digestives au CHU du Point-G. Mali Medical, 27, 19-22.
[19]
Harissou, A., Ibrahim, A.M., Oumarou, H., Mansour, A., Amadou, M., Ousseni, E.A., et al. (2015) Retard diagnostique et implication pronostique en milieu africain. Cas des urgences en chirurgie digestive à l’Hôpital national de Zinder, Niger. European Scientific Journal, 11, 251-262.
[20]
Ouangre, E., Zida, M., Bonkoungou, P.G., Sanou, A. and Traoré, S.S. (2013) Les péritonites aigües généralisées en milieu rural au Burkina Faso: à propos de 221 cas. Revue Africaine et Malgache de Recherche Scientifique/Sciences de la Santé, 1, 75-79.
[21]
Lopez, N., Kobayashi, L. and Coimbra, R. (2011) A Comprehensive Review of Abdominal Infections. World Journal of Emergency Surgery, 6, 7. https://doi.org/10.1186/1749-7922-6-7
[22]
Sartelli, M., Viale, P., Koike, K., et al. (2011) WSES Concensus Conference: Guideline for First-Line Management of Intra-Abdominal Infections. World Journal of Emergency Surgery, 6, 2. https://doi.org/10.1186/1749-7922-6-2
[23]
Michel, F., Leone, M. and Martin, C. (2015) Prise en charge du sepsis grave et du choc septique: Survivre au sepsis. Le Praticien en Anesthésie Réanimation, 19, 147-152. https://doi.org/10.1016/j.pratan.2015.04.003
[24]
Kanté, L., Diakité, I., Togo, A., Dembélé, B.T., Traoré, A., Maiga, A., et al. (2013) Péritonites aiguës généralisées à l’hôpital SOMINE DOLO DE MOPTI: Aspects épidémiologique et thérapeutique. Mali Medical, 28, 20-23.
[25]
Rasamoelina, N., Rajaobelison, T., Ralahy, M.F., Riel, A.M., Rabarijaona, M., Solofomalala, G.D., et al. (2010) Facteurs de mortalité par les urgences digestives dans le service de réanimation du CHU de Fianarantsoa Madagascar. Revue D’anesthésie-Réanimation et de Médecine D’urgence, 2, 10-11. https://doi.org/10.1007/s12157-017-0706-8