Primary Biliary Cholangitis – Case Report and Review of Literature

Sa？etak Primary biliary cirrhosis (PBC), also known as primary biliary cholangitis, is an autoimmune disorder that belongs to the group of cholestatic liver diseases. PBC is a chronic inflammatory liver disease that can lead to liver fibrosis and cirrhosis and the development of hepatocellular carcinoma. Understanding the biology of PBC is important to ensure effective patient care, improve therapeutic options and provide targeted treatment. PBC is typically a disease that requires lifelong therapy aimed at preventing the progression of the liver disease and at reducing or eliminating the symptoms that impair patients’ quality of life. In everyday clinical practice, PBC should be considered in all patients with elevated cholestasis parameters, especially if they last longer than 6 months. The paper presents a case of a female patient suffering from PBC with a persistent diagnosis and demanding treatment