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-  2019 

Outcomes in patients with heart failure with regard to statin therapy

DOI: 10.15836/ccar2019.222

Keywords: heart failure, statin therapy, outcome

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Abstract:

Sa?etak Objective: The aim of this study was to investigate whether statin therapy influenced outcomes in patients with acute heart failure (HF).1,2 Patients and Methods: Eighty five patients with diagnosis of HF were included in the study. For each patient the following data were obtained: gender, age, comorbidities and medications. New York Heart association (NYHA) class for heart failure was determined by physician evaluation and left ventricle ejection fraction (LVEF) was determined by echocardiography. Outcome points were: hospitalization, in-hospital death, mortality after 6 months, 1 year and 2 years. All-cause mortality included cardiovascular events or worsening heart failure. Results: Mortality after 6 months, 1 year and 2 years was the most frequent in patients without statin therapy with a statistically significant difference (p = 0.001). Progression of HF accounted for 31.7% of mortality in patients without statin therapy. Conclusion: Statin therapy is associated with substantially better long-term outcomes in patients with HF

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