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- 2020
A BRAF V600E Mutation in RET-Negative Medullary Thyroid CancerDOI: https://doi.org/10.1155/2020/7641940 Abstract: We report the case of a woman with a sporadic medullary thyroid carcinoma. Genomic analysis found that her tumor did not contain any common RET mutations but did harbor a BRAF V600E mutation. Only one other well-confirmed example of the BRAF V600E mutation has been reported in an MTC patient. We conclude that this common BRAF mutation may independently drive neoplastic transformation of human parafollicular C cells
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