Synthesis and Herbicidal Activity Against Buffelgrass (Cenchrus ciliaris) of (±)-3-deoxyradicinin

A novel synthetic strategy for obtainment of (±)-3-deoxyradicinin ( 2) is reported. This synthetic methodology is more efficient than those previously reported in the literature and also shows higher versatility towards the introduction of different side-chains at both C-7 and C-2. The obtained compound (±)- 2 shows phytotoxicity against the grass-weed buffelgrass comparable to that of the natural phytotoxin radicinin ( 1). Therefore, (±)- 2 can constitute a more practical synthetic alternative to 1 as bioherbicide for buffelgrass control. View Full-Tex