Level of Cardiac Biomarkers in Immediate Post-Operative Period after Off-Pump CABG and Its Comparison with On-Pump CABG: A Prospective Analytical Study
Background: Coronary artery
bypass grafting (CABG) is an important modality of treatment for ischemic heart
disease. Both off-pump and on-pump CABG have direct effect on the level cardiac
biomarkers in the perioperative period. The use of cardiopulmonary bypass (CPB)
and aortic cross-clamping may cause additive myocardial damage leading to
further elevation of blood markers. The present study is aimed at measuring and
comparing the cardiac biomarker levels in immediate post-operative period after
on-pump CABG (ONCAB) and off-pump CABG (OPCAB). Methods: All the patients who
underwent CABG from January 2015 to June 2016 on elective or emergency basis at
Nilratan Sircar Medical College & Hospital have been included in the study.
Total 106 patients were operated for CABG of which 75 patients were operated
for OPCAB and 31 patients were operated for ONCAB.For the comparison of
data the blood markers Troponin-T (Trop-T) and Creatine Kinase-MB (CK-MB) are
measured during anesthesia before surgery, post-operatively
after 1hour, post-operatively after 4hours and post-operatively after 20hours. All recorded data are analyzed using standard statistical methods. Results:We found the markers are
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