Epidermolysis Bullosa (EB) is a group of rare genetic skin conditions, which is characterised by extremely fragile skin and recurrent blister formation, resulting from minor mechanical friction or trauma. Sufferers of EB have compared the sores to third-degree burns. Stevens-Johnson syndrome is a rare but very serious skin problem, which causes the appearance of reddish lesions throughout the body and other changes, such as difficulty in breathing and fever, which can endanger the life of the affected person. The aim of this study was to show efficacy of a NANOSKIN ACT, AND NANOSKIN ACT SOFT wound dressing on the wound care management in patients with EB AND Stevens-Johnson syndrome (SJS).
References
[1]
Fine, J.D. (2010) Inherited Epidermolysis Bullosa: Past, Present, and Future. Annals of the New York Academy of Sciences, 1194, 213-222.
https://doi.org/10.1111/j.1749-6632.2010.05463.x
[2]
Pai, S. and Marinkovich, M.P. (2002) Epidermolysis Bullosa: New and Emerging Trends. American Journal of Clinical Dermatology, 3, 371-380.
https://doi.org/10.2165/00128071-200203060-00001
[3]
Pope, E., Lara-Corrales, I., Mellerio, J., et al. (2012). A Consensus Approach to Wound Care in Epidermolysis Bullosa. Joint American Academy of Dermatology, 67, 904-917. https://doi.org/10.1016/j.jaad.2012.01.016
[4]
Denyer, J. and Pillay, E. (2012) Best Practice Guidelines for Skin and Wound Care in Epidermolysis Bullosa. International Consensus. DEBRA.
https://www.woundsinternational.com/download/resource/5978
[5]
Dhivya, S., Padma, V.V. and Santhini, E. (2015) Wound Dressings—A Review. Biomedicine (Taipei), 5, 22. https://doi.org/10.7603/s40681-015-0022-9
[6]
Cowan, L.J. and Stechmiller, J. (2009) Prevalence of Wet-to-Dry Dressings in Wound Care. Advances in Skin & Wound Care, 22, 567-573.
https://doi.org/10.1097/01.ASW.0000363469.25740.74
[7]
Ellender, R.P., Peters, C.W., Albritton, H.L., Garcia, A.J. and Kaye, A.D. (2014) Clinical Considerations for Epidermal Necrolysis. Ochsner Journal, 14, 413-417.
https://www.ncbi.nlm.nih.gov/pubmed/25249808
[8]
Mockenhaupt, M. (2014) Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Clinical Patterns, Diagnostic Considerations, Etiology, and Therapeutic Management. Seminars in Cutaneous Medicine and Surgery, 33, 10-16.
https://doi.org/10.12788/j.sder.0058
[9]
Schwartz, R.A., McDonough, P.H. and Lee, B.W. (2013) Toxic Epidermal Necrolysis: Part I. Introduction, History, Classification, Clinical Features, Systemic Manifestations, Etiology, and Immunopathogenesis. Joint American Academy of Dermatology, 69, 173.e1-13. https://doi.org/10.1016/j.jaad.2013.05.003
[10]
Lee, H.Y. and Chung, W.H. (2013) Toxic Epidermal Necrolysis the Year in Review. Current Opinion in Allergy and Clinical Immunology, 13, 330-336.
https://doi.org/10.1097/ACI.0b013e3283630cc2
[11]
Al Mualla, S., Farahat, R., Basmaji, P., de Olyveira, G.M., Costa, L.M.M., da Costa Oliveira, J.D. and Francozo, G.B. (2018) Special Nanoskin-ACT-Biological Membranes from Deep Wounds. Journal of Biomaterials and Nanobiotechnology, 9, 79-88.
