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COVID-19防治与硒营养关系研究与探讨
Study on the Relationship between COVID-19 Control and Selenium Nutrition

DOI: 10.12677/HJAS.2020.105040, PP. 263-272

Keywords: COVID-19，发病率，治愈率，硒营养，免疫力
COVID-19, Incidence Rate, Cure Rate, Selenium Nutrition, Immunity

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Abstract:

以2月2日至2月29日湖北省卫计委对外发布的疫情数据为依据，分析和探讨了COVID-19防治与人体硒营养水平的关系。研究表明，湖北省COVID-19的传播与疫情发展具有明显的空间分布特征，不同分区距武汉市的空间距离与发病率之间呈极显著负相关(R = ？0.9933, P < 0.01)；不同分区间的发病率差异达极显著水平(P < 0.01)；发病率曲线在2月15日之前呈明显上升趋势，且曲线斜率I区 > II区 > III区 > IV区。湖北省发病率最低的是恩施州，与恩施同区域的十堰和与恩施紧邻的宜昌的发病率分别较恩施高122.33%、186.24%，恩施的发病率极显著低于十堰和宜昌(P < 0.01)。湖北省治愈率最高的是恩施州，与武汉紧邻的黄冈、咸宁在对口重点医疗援助下，其治愈率于2月19日之后上升到恩施的同一水平。与恩施同区域的十堰和与恩施紧邻的宜昌的平均治愈率分别较恩施低19.88%、35.81%，恩施的治愈率极显著高于十堰和宜昌(P < 0.01)。恩施土壤硒含量均值达3.758 mg/kg，被誉为“世界硒都”，农作物的硒含量显著高于缺硒区域，全血硒含量均值为0.093~0.302 μg/mL，达到硒营养良好状态。在疫情防控条件相似和相对封闭的特定区域内，COVID-19肺炎发病率和治愈率两项特征指标都指向COVID-19疫情与人体硒营养水平具有密切关系，为增加补硒措施以完善诊疗方案提供了依据。在目前尚无特效药或疫苗的情况下，提出了对确诊患者、疑似病例和易感人群开展补硒工作的建议。
Based on the epidemic data released by Hubei Provincial Health and Family Planning Commission from February 2 to February 29, the relationship between COVID-19 prevention and human selenium nutrition level was analyzed and discussed. Studies have shown that the spread of COVID-19 and the development of epidemic situation in Hubei Province have obvious spatial distribution characteristics, and the spatial distance between different districts and Wuhan city is extremely significantly negatively correlated with the incidence rate (R = ？0.9933, P < 0.01). The difference in the incidence rates by sub-area reached a very significant level (P < 0.01); the incidence rate curve showed a clear upward trend before February 15, and the slope of the curve was Area I > Area II > Area III > Area IV. The lowest incidence rate in Hubei Province is Enshi Prefecture. The incidence rates of Shiyan in the same area as Enshi and Yichang in the immediate vicinity of Enshi are 122.33% and 186.24% higher than Enshi, respectively. The incidence of Enshi is significantly lower than Shiyan and Yichang (P < 0.01). The highest cure rate in Hubei Province is Enshi Prefecture. Huang-gang and Xianning, which are close to Wuhan, have received the corresponding medical assistance. Their cure rate rose to the same level as Enshi after February 19. The average cure rates of Shiyan in the same area as Enshi and Yichang in the immediate vicinity of Enshi were 19.88% and 35.81% lower than that of Enshi respectively. The cure rate of Enshi was significantly higher than that of Shiyan and Yichang (P < 0.01). The average selenium content of Enshi soil is 3.758 mg/kg, which is known as the “world selenium capital”. The selenium content of crops is significantly higher than that of selenium-deficient areas. The average selenium content of

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