基于文献文本挖掘的广西临床常用特色鲜药药性分布规律研究
Research on the Distribution of Medicinal Properties of Guangxi Clinical Characteristic Fresh Herbs Based on Literature Mining

目的：研究广西临床常用鲜药药性分布规律，为鲜药的开发和临床应用提供参考。方法：在《桂本草》和《广西海洋药物》中检索临床常用中药，建立纳入和排除标准筛选鲜药，运用Excel 2010建立临床常用中药总数据库1个，子数据库6个(鲜药子数据库、四气子数据库、五味子数据库、归经子数据库、毒性子数据库、功效子数据库)，然后对6个子数据库的数据进行频数和频率分析。结果：共检索出292味临床常用中药，经纳入、排除筛选，最终纳入174味鲜药，其中鲜植物药164味，鲜动物药10味。鲜药药性以寒性、凉性、平性药为主；药味以苦、甘、辛为主，鲜动物药以咸为主；归经以肝、肺、脾、胃为主；有明确毒性记载的有21味，鲜植物药18味，鲜动物药3味；鲜植物药的功效主要为清热、解毒、祛风、祛湿、消肿、活血、止血、散瘀、止痛，鲜动物药主要功效为祛风、活血、清热、祛湿、散瘀、解毒、消肿。结论：从整体上来看，鲜药多性寒凉味苦、甘、辛，主入肝、肺、脾、胃经，主要功效为清热、解毒、祛风、祛湿、活血、消肿，临床使用时应综合考虑鲜药的药性和功效，并针对鲜植物药和鲜动物药加以区分。
Objective: To study the distribution of medicinal properties of fresh drugs in Guangxi, and to pro-vide reference for the development and clinical application of fresh drugs. Methods: In Compendium of Material Medica and Guangxi Marine Medicine, Chinese traditional medicines commonly used in clinical practice were searched. Establish inclusion and exclusion criteria for screening fresh herbs, Use Excel 2010 to establish a database, including a general database of commonly used traditional Chinese medicine, 6 sub-databases, including sub-databases of fresh medicines, Siqi sub-database, Schisandra database, Guijing sub-database, toxicity sub-database, efficacy sub-database. And the frequency and frequency analysis of the data of 6 sub-databases were analyzed. Results: A total of 292 commonly used traditional Chinese medicines were retrieved, and 174 fresh medicines were finally included after inclusion and exclusion screening, among which 164 were fresh plant medicines and 10 were fresh animal medicines. The medicinal properties of fresh medicine are mainly cold, cool and even. The taste of medicine is bitter, sweet and spicy, while the taste of fresh animal medicine is salty. Liver, lung, spleen and stomach were the main meridians. There were 21 drugs with clear toxicity records, 18 fresh plant drugs and 3 fresh animal drugs. The main efficacy of fresh plant medicine is to clear heat, detoxify, dispel wind, clear damp, reduce swelling, promote blood circulation, stop bleeding, disperse blood stasis and relieve pain. The main efficacy of fresh animal medicine is to dispel wind, promote blood circulation, clear heat, clear damp, disperse blood stasis, detoxify and reduce swelling. Conclusion: On the whole, Fresh herbs are mostly cold, with bitter, sweet, and xin flavors. They are mainly returned to the liver, lungs, spleen, and stomach meridian. The main effects include clearing heat, detoxifying, expelling wind, removing dampness, promoting blood circulation, and reducing swelling. The clinical use of fresh herbs should comprehensively consider his medicinal